海南医科大学学报

目的:探讨肝病患者血清总胆汁酸和胆碱酯酶水平测定的临床意义。方法:测定肝病患者(138例)和正常对照组(76例)空腹血清总胆汁酸和胆碱酯酶的水平,并进行比较。结果:与正常对照组相比,除慢性迁延性肝炎外,急性肝炎、慢性活动性肝炎、肝硬化、肝癌患者血清总胆汁酸水平明显升高(P<0.01),胆碱酯酶水平明显降低(P<0.01)。结论:肝病患者测定血清总胆汁酸和胆碱酯酶水平,可以反映肝实质损害的程度,有助于了解急性肝病的恢复情况,在慢性肝病的预后等方面有很高的价值。

Objective: To discuss the significance of TBA and CHE evaluation.Methods: Fasting TBA and CHE were evaluated and compared between 138 patients with liver diseases and 76 healthy volunteers.Results: The TBA level of the healthy control group is significantly lower than that of the disease group including patients with chronic active hepatitis,acute hepatitis,liver cirrhosis,or liver cancer;while the CHE level is significantly higher(P<0.01).There is an exception for patients with chronic persistent hepatitis.Conclusion: Evaluation of TBA and CHE is of great significance in the prognosis of chronic liver diseases because they can reflect the degree of liver damage.