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毛蕊异黄酮葡萄糖苷(Calycosin-7-O-β-D-glucoside,CG)属于异黄酮类化合物,是豆科植物蒙古黄芪和荚膜黄芪干燥根提取出来的活性单体成分,也是国民常用中药黄芪的最具活性的主要成分之一,具有明显的抗氧化、抗病毒、抑制黑色素形成和免疫抑制等作用。现代科技日臻精进,中药单体辅助甚至代替合成药物治疗已然成为世界医学的重要课题。近年,随着对CG作用机制研究的不断深入,人们发现其药理作用非常广泛,如CG的抗肿瘤作用,对心脑血管疾病的作用等。本文就有关CG的药理作用及最新研究进展做简要综述。
Abstract：The isoflavone compound calycosin-7-O-β-D-glucoside(CG)is an active monomer component extracted from the dry roots of the leguminous plant Astragalus mongolicus and Astragalus.It is also one of the main active ingredients in the Astragalus that is a commonly used traditional herbal.CG has obvious effects of anti-oxidation,anti-virus,inhibition of melanin formation,and immunosuppression.With the advancement of modern technology,it has become a pivotal subject that the monomer of Chinese herb assists or even substitutes the synthetic drug in medical field.In recent years,with the deepening of research on the mechanism of action of CG,which has been found that its pharmacological effects are very extensive,such as the anti-tumor effect and the effect on cerebrovascular diseases of CG.This review summarizes the pharmacological effects and the latest research progress of CG.
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基本信息:
DOI：10.13210/j.cnki.jhmu.20191223.001
中图分类号:R285
引用信息:
[1]李亮亮,黄金智.毛蕊异黄酮葡萄糖苷药理作用的研究进展[J].海南医学院学报,2020,26(02):156-160.DOI:10.13210/j.cnki.jhmu.20191223.001.
基金信息:
广东省中医药局面上项目基金(20191192)~~
2019-12-23
2019-12-23
2019-12-23