海南医科大学学报

目的:探讨不同用药方案对于治疗念珠菌性阴道炎所产生的经济学效果。方法:236例门诊念珠菌性阴道炎患者随机分为4组,分别给予克霉唑阴道片(凯妮汀)1个疗程1 d(A组),阴道用盐酸特比奈芬阴道泡腾片1个疗程7 d(B组),阴道用硝酸咪康唑栓1个疗程7 d(C组),克霉唑阴道片(国产)1个疗程6 d(D组),运用药物经济学方法进行成本-效果分析。结果:4组有效率分别为90.91%、89.47%、78.18%和83.93%;成本分别为45.51元、58.80元、18.91元和23.95元;成本-效果比分别为0.50、0.66、0.24、0.29;A组增量成本-效果比为2.09,B组增量成本-效果比为3.53,D组增量成本-效果比为0.88。结论:D组成本较低且疗效好。

Objective: To eva1uate the economic effectiveness of different therapeutic schemes for candidal vaginitis.Methods:A total of 236 outpatients with candidal vaginitis were randomly divided into 4 groups:Group A were assigned to receive Clotrimazole Vaginal Tablets(Gyno Canesten) for 1 day;Group B to receive Terbinafine Hydrochloride Vaginal Effervescent Tablets for 7 days;Group C to receive Miconazole Nitrate Suppositories for 7 days;and Group D to receive Clotrimazole Vaginal Tablets(Made in China) for 6 days.Cost-effectiveness analysis pharmacoeconomics was conducted to analyze the four treatments.Results:The effective rates for Group A,B,C and D were 90.91%、89.47%、78.18% and 83.93%,respectively,the total costs in the 4 groups were 45.51 yuan,58.80 yuan,18.91 yuan and 23.95 yuan,respectively;and the cost-effectiveness ratios were 0.50,0.66,0.24 and 0.29,respectively.As compared with Group C,the increment cost-effectiveness ratios for Group A,B and D were 2.09,3.53,0.88 respectively.Conclusions:Group D(Clotrimazole Vaginal Tablets which Made in China)is the best treatment regarding to aspect of cost-effectiveness.