海南医科大学学报

目的:了解感染了人类免疫缺陷病毒(HIV)人群中的乙肝病毒、丙肝病毒和梅毒的携带情况。方法:采用酶联免疫吸咐试验(ELISA)检测206例(男性138例,女性68例)HIV阳性血清中HBV、HCV,采用TPPA法进行梅毒试验,比较HIV感染者及不同性别感染者HBV、HCV、梅毒感染率。结果:206例患者HCV感染率(34.47%)明显高于HBV和梅毒感染率(18.93%、16.99%),女性梅毒、HBV+梅毒、HCV+梅毒检出率均明显高于男性(P均<0.05)。结论:感染HIV时往往合并丙肝、乙肝和梅毒的二重或多重感染;HIV/HCV混合感染明显高于HIV/HBV和HIV/梅毒混合感染,女性HIV/梅毒混合感染明显高于男性;治疗HIV的同时注意乙肝、丙肝、梅毒多重感染的防治。

Objective: To investigate the incidence of of HIV1 +2 cases with hepatitis Bvirus B,hepatitis C virus and syphilis.Methods: A total of 206 HIV positive cases(138 male cases,68 female cases)were determined by enzyme immunosorbent assay(ELISA) method in for hepatitis C virus and hepatitis B virus.They were determined by TPPA methods for syphilis.Results: A total of 71 patients(34.47%) carried hepatitis C virus,39 cases(18.93%) carried hepatitis B virus,and 35 cases(16.99%) carried syphilis virus.The infection rate of hepatitis C virus was significantly higher(P<0.05).And more female patients were infected.Conclusions: when infected with HIV,patients usually have complication of by double or multiple infections of hepatitis C,hepatitis B and syphilis.The incidence of mixed infection of HIV and HCV is significantly higher than that of HIV/HBV mixed infection and HIV/syphilis.The incidence is higher in female patients.The attention should be paid to the prevention of multiple infections of hepatitis B,C and syphilis in the treatment of HIV.