海南医科大学学报

目的:探讨结直肠癌同时性肝转移的外科治疗效果。方法:收集1996年1月～2006年1月外科治疗42例结直肠癌肝转移患者的临床资料,根据治疗方法分为同期肝转移灶切除组(A组)22例;肝转移灶未切除组(B组)20例,其中6例行肝动脉化疗泵灌注化疗,14例行介入治疗。结果:A组术后1、3、5年生存率分别为90.9%、54.6%、27.3%;B组术后1年生存率为70.0%,3年和5年生存率为0。两组术后生存时间差异有统计学意义(P<0.05)。两组术后并发症差异无统计学意义(P>0.05)。结论:同时性肝转移患者同期肝转移灶切除预后较好,并不增加术后并发症。

Objective:To investigate the effect of surgical treatment on colorectal carcinoma with synchronous liver metastases.Methods:From January 1996 to January 2006,42 cases of colorectal carcinoma with synchronous liver metastases were collected,including 22 patients underwent simultaneous liver metastatic tumor resections(Group A),and 20 cases without resection(Group B),in which 6 patients had chemotherapy by hepatic arterial infusion,and 14 patients had intervenient therapy.Results:The survival rates after 1,3,5-year in Group A were 90.91%,54.55%,and 27.27% respectively,while the rates in Group B were 70.00%,0%,and 0% respectively.There were significant differences between the two groups,while there were no significant differences in incidence of there postoperative complications.Conclusion:Patients with simultaneous liver and colorectal resection had better prognosis,and without higher incidence of postoperative complications.