海南医科大学学报

目的:了解三亚地区非淋菌性尿道炎(NGU)女性患者中支原体感染情况,分析支原体对常用抗生素的敏感性。方法:采集360例疑似NGU患者的尿道或宫颈分泌物标本,采用IST试剂盒进行解脲支原体(UU)和人型支原体(MH)选择性培养和鉴定,用药物敏感试验所分离的支原体对10种抗生素的敏感性。结果:360例标本中,支原体阳性208例,总阳性率为57.8%(208/360)。获得明确鉴定结果的185例患者中,UU、MH及UU+MH混合感染分别为84.4%、3.2%、1.9%。结论:支原体是三亚地区NGU患者主要病原体之一,其中UU是引起NGU最主要的支原体,强力霉素和美满霉素仍是三亚地区分离的UU和MH最为敏感的抗生素。

Objective:To investigate mycoplasma infection in female patients with nongonococcal urethritis(NGU),and explore sensitivity of mycoplasm to common antibiotics.Methods:Collected urethral and cervical secretion samples of 360 suspicious patients with NGU,made selective culture and identification of urea plasma urealyticum(UU)and mycoplasma hominis(MH)by IST kit.Analyzed sensitivity of isolated mycoplasm to 10 different antibiotics.Results:208 out of 360 cases had positive mycoplasm infection,with positive rate as 57.8%(208/360).185 cases had confirmed identification,and the incidence of UU,MH infection and combination infection of UU and MH were 84.4%,3.2% and 1.9% respectively.Conclusion:Mycoplasm is one of main pathogens of NGU in Sanya district,with UU as main mycoplasm,and UU and MH are most sensitive to doxycycline and minocycline hydrochloride.