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溃疡性结肠炎的发病率逐年增加，但发病机制仍未完全明朗，广大学者分别从遗传因素、环境因素、肠道微生态失衡、肠黏膜屏障紊乱、异常免疫应答和线粒体病等方面进行研究，为进一步了解溃疡性结肠炎可能存在的发病机理，现将其研究进展进行综述，以期更好地指导临床用药，同时为进一步研究其发病机制提供新思路。
Abstract：The incidence of ulcerative colitis is increasing year by year,yet the pathogenesis is still not clear. Many schol-ars have studied the genetic factors,environmental factors,intestinal microecological imbalance,intestinal mucosal barrier disor-der,abnormal immune response and mitochondrial diseases,and abundant achievements have been made. In order to further un-derstand the possible pathogenesis of ulcerative colitis,this paper reviews its research progress,in order to better guide clinical medication,and provide new ideas for further study of its pathogenesis.
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基本信息:
DOI：10.13210/j.cnki.jhmu.20210430.002
中图分类号:R574.62
引用信息:
[1]谢晶日,陈善涛,刘芝伟.溃疡性结肠炎发病机制研究进展[J].海南医学院学报,2022,28(23):1835-1840.DOI:10.13210/j.cnki.jhmu.20210430.002.
基金信息:
国家中医药管理局全国名老中医药专家传承工作室建设项目（国中医药人教函[2016]42号）~~
2021-04-30
2021-04-30
2021-04-30