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健康的育龄女性阴道内存在的微生物种类繁多，其中乳酸杆菌为主要菌群，是维持阴道微生态平衡的重要角色。当阴道内的酸碱度失衡、菌群结构紊乱、局部免疫功能下降等情况发生时，阴道微生态平衡则容易被破坏，甚至发生阴道感染。阴道微生态紊乱不仅影响女性生活质量，还与女性妊娠期的不良妊娠结局存在相关性，影响母婴健康。因此，本文就妊娠期阴道微生态情况及其与妊娠结局相关性研究进展做一综述。
Abstract：The vaginal microbiota of healthy women of reproductive age is characterized by a wide variety of microorganisms, with Lactobacilli being the predominant group. Lactobacilli play an important role in maintaining the balance of vaginal microbiota. When there is an imbalance in the acidity and alkalinity of the vagina, a structural disorder in the bacterial community, or a decrease in local immune function, the balance of the vaginal microbiota is easily disrupted,and even vaginal infections occur. The disturbance of vaginal microbiota not only affects women's quality of life, but also has a correlation with adverse perinatal outcomes during pregnancy, affecting maternal and fetal health. Therefore, this article provides a comprehensive review of the research on the vaginal microbiota during pregnancy and its correlation with perinatal outcomes.
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基本信息:
DOI：10.13210/j.cnki.jhmu.20231121.001
中图分类号:R714
引用信息:
[1]徐小惠,马宁,卢伟英.妊娠期阴道微生态与妊娠结局相关性研究进展[J].海南医学院学报,2024,30(11):873-880.DOI:10.13210/j.cnki.jhmu.20231121.001.
基金信息:
国家自然科学基金资助项目（82260304）; 海南省重点研发项目（ZDYF2022SHFZ074）~~
2023-11-22
2023-11-22
2023-11-22