海南医科大学学报

目的:观察中药配合综合干预对高血压病的防治作用。方法:回顾分析2013年10~12月于我院就诊的病历资料完整的高血压病患者120例,依据入院先后分为观察组与对照组,观察组患者在常规治疗的基础上加用菊明颗粒配合综合干预治疗,对照组只采用常规治疗;两组患者均治疗8周,并每3个月随访1次,共随访1年,评价菊明颗粒配合综合干预对高血压病的防治作用及对患者生活的影响。结果:两组患者干预治疗后收缩压(SBP)、舒张压(DBP)均较干预治疗前显著下降,干预治疗前后比较差异有统计学意义(P<0.05);观察组干预治疗后SBP、DBP下降较对照组更为显著,组间比较差异有统计学意义(P<0.05);观察组患者治疗总有效率显著高于对照组(P<0.05);两组患者治疗后中医证候积分均较治疗前显著下降(P<0.05),观察组干预治疗后中医证候积分下降较对照组更为显著(P<0.05);观察组患者生理职能(role-physieal,Rp)、情感职能(role-Emotional,RE)、躯体疼痛(bodily Paln,Bp)与治疗前比较显著提高(P<0.05);对照组患者干预后RE较治疗前显著提高(P<0.05);两组患者治疗后各维度均无统计学差异(P>0.05)。结论:中药配合综合干预可有效控制患者血压,改善患者中医证候积分及生活质量,效果显著。

Objective:To observe the effect of traditional Chinese medicine combined with comprehensive intervention on hypertension.Methods:A total of 120 hypertensive patients admitted in our hospital from October 2013 to December 2013 were enrolled and divided into the observation group and the control group according to the admitted time.The patients in the observation group were given with Ju-Ming granules combined with comprehensive intervention based on the conventional treatment;while patients in the control group only received conventional treatment.The patients in the two groups were treated for 8 weeks.They were followed up every three week for one year.The effect of Ju-Ming granules combined with comprehensive intervention on hypertension and the effect on patients' living qualities were evaluated.Results:The SBP and SDP in the patients of the two groups were significantly reduced after interventional treatment(P<0.05).The SBP and SDP in the observation group were significantly reduced compared with the control group,(P<0.05).The total effective rate in the observation group was significantly higher than that in the control group(P<0.05).The TCM syndrome scores in the two groups after treatment were significantly decreased when compared with those before treatment(P<0.05).The TCM syndrome score reduction in the observation group after interventional treatment was more obvious than that in the control group(P<0.05).The scores of physiological function,emotional function,and body pain were significantly elevated in the observation group when compared with those before treatment(P<0.05);and the score of emotional function in the control group after treatment was significantly higher than that before treatment(P<0.05).The differences in various dimensions of two groups after treatment were not statistically significant(P>0.05).Conclusions:It can be concluded that traditional Chinese medicine combined with comprehensive intervention can effectively improve patients' hypentension status,TCM syndrome scores and living qualities.