海南医科大学学报

目的::探究妊娠期糖尿病患者中糖化血红蛋白的筛查意义。方法:选取我院产前门诊检查的孕妇220例,比较各种糖尿病筛查诊断敏感、特异性。结果:GDM组HbAlc(9.8±0.4)%;OGTT(9.2±0.3)mmol/L;FPG(9.6±0.7)mmol/L,较正常妊娠组显著增高,差异具有统计学意义(P<0.05)。在GDM筛查中HbAlc敏感性、可靠性、特异性、阳性预测为93.1%、98.0%、98.4%、81.8%,指标对比OGCT、FPG均高。结论:HbA1c在GDM患者中可实用、简单、快速、不易受干扰检测,敏感性、特异性高,在GDM筛查中具应用价值。

Objective: To explore significance of screening glycated hemoglobin in patients with gestational diabetes mellitus.Methods: A total of220 cases of pregnant women visiting outpatient during 2012 January-March were selected.Diagnostic sensitivity and specificity of various diabetes screening were compared.Results: In the GDM group HbAlc was(9.8± 0.4) %,OGTT was(9.2±0.3) mmol/L,FPG was(9.6 ±0.7) mmol/L,which were increased significantly compared with normal pregnancy group(P<0.05).Sensitivity,reliability,specificity,positive predictive rate of HbAlc in GDM screening were 93.1%,98%,98.4%,81.8%,respectively,which were higher than those of OGCT,FPG.Conclusions: HbA1c is practical,simple,rapid,less susceptible to interference detection,and is of high sensitivity and specificity.It is valuanle in GDM screening.