海南医科大学学报

目的:探讨针刺疗法辅助治疗难治性失眠症的疗效与安全性。方法:将100例难治性失眠症患者随机分入观察组和对照组,每组50例。两组均给予劳拉西泮+多塞平+中药解郁安神颗粒口服,设置相同的心理治疗,观察组另增加针刺治疗,观察8周。用匹茨堡睡眠质量指数量表(PSQI)和副反应量表(TESS)分别评定临床疗效和不良反应。结果:在治疗后第4、8周末,观察组痊愈率和显效率均高于对照组,第4周末有效率也高于对照组;PSQI评分低于同期对照组;差异有统计学意义(P均<0.05),但有效率差异无统计学意义,两组TESS评分无显著差异。结论:针刺疗法对难治性失眠症有较好的辅助治疗作用,临床使用安全。

Objective: To explore the efficacy and safety of acupuncture in auxiliary treatment of the refractory insomnia.Methods: All 100 patients with refractory insomnia were randomly assigned toobservation group and control group by half.All cases were treated with lorazepam and doxepin combining withIieyu′anshen particles.And the psychotherapy was given to patients of two groups.In addition,the patients in the observation group received a treatment of acupuncture for 8 weeks.The Pittsburgh Sleep Quality Index(PSQI) and Treatment Emergent Side effect Scale(TESS) were used to evaluate the efficacy and adverse effect,respectively.Results: In the 4th and 8th weekend after treatment,the rates of cure and marked improvement in the observation group were significantly higher than those in the control group(P<0.05).So was the efficacy rate in the 4th weekend.After treatment,the scores of PSQI in the observation group were significantly lower than.But there was no significant difference in scores of TESS between the two groups.Conclusions: Acupuncture is effective and safe in auxiliary treatment of the refractory insomnia without adverse effect.