海南医科大学学报

目的:探讨超声心动图评价室间隔缺损(VSD)和患者经导管封堵术后心脏结构、血流动力学和心功能的变化。方法:经胸超声心动图检查确诊为VSD 100例,成功施行VSD封堵术的患者99例。于术前、术后48h、术后1、3、6个月、1年,采用经胸超声心动图(TTE)测定其心脏结构、血流动力学及心功能指标。结果:术后1个月组及以后各组较术前组左房、左室内径减小,差异具有统计学意义(P<0.05);术后48h组及以后各组较术前组肺动脉瓣口血流速度、二尖瓣口血流速度、肺动脉收缩压、左室射血分数减小,差异具有统计学意义(P<0.05)。结论:VSD介入封堵术不仅可有效根治先天性解剖畸形,而且早期迅速纠正血流动力学异常,改善左心几何构型和心功能。

Objective:To evaluate changes of cardiac morphology and function after undergoing transcatheter closure of ventrial septal defect by transthoracic echocardiography.Methods:A total of 100confirmed VSD cases were enrolled,of which 99underwent transcatheter closure of VSD successfully.Follow up was conducted to evaluate the cardiac morphology,the cardiac hemodynamic and the cardiac function by transthoracic echocardiography(TTE)before undergoing the operation,1,3,6months and 1year after undergoing the operation.Results:The diameter of left atrial,left ventricular decreased significantly one month after undergoing the operation(P<0.05).Pulmonary valve blood flow velocity,mitral orifice blood flow velocity,pulmonary artery,left ventricular ejection fractional decreased significantly from 48hours after the procedure(P<0.05).Conclusions:Transcatheter closure of VSD can effectively repair congenital anatomic deformity,and correct hemodynamic abnormalities rapidly in the early stage.Meanwhile,it reconstructs left heart geometry and improve heart function significantly.