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慢性萎缩性胃炎以其高发病率、高癌变率受到临床广泛关注,目前现代医学缺乏针对慢性萎缩性胃炎的有效治疗方案,而中医药治疗该病多能改善临床症状和实验室指标、病理检查结果,提高患者生存质量。魏玮教授在临床中运用"调枢通胃"法治疗慢性萎缩性胃炎,以半夏泻心汤为底方,灵活加减,辛开苦降,疏肝活血,配合多种外治法以及心理建设,取得较为满意的临床疗效。
Abstract:Chronic atrophic gastritis has attracted wide attention in clinic due to its high incidence rate and high canceration rate. At present, modern medicine lacks an effective treatment scheme for chronic atrophic gastritis. Traditional Chinese medicine can improve clinical symptoms, laboratory indexes, pathological examination results and patients' quality of life for patients with chronic atrophic gastritis. Professor Wei used the method of "balancing digestive functions by regulating pivot" to treat chronic atrophic gastritis in clinical practice. With flexible addition and subtraction on the basic prescription Banxia Xiexin decoction and coordination with various external treatment methods and psychological construction, professor Wei has achieved satisfactory clinical effects with the pungent-opening and bitter-descending method and dispersing liver and promoting blood circulation method.
1 李军祥,陈誩,吕宾,等.慢性萎缩性胃炎中西医结合诊疗共识意见(2017年)[J].中国中西医结合消化杂志,2018,26(2):121-131.
2 房静远,杜奕奇,刘文忠,等.中国慢性胃炎共识意见(2017年,上海)[J].胃肠病学,2017,22(11):670-687.
3 魏玮,荣培晶,陈建德,等.“调枢通胃”理论的探讨与构建[J].中医杂志,2018,59(6):474-477,502.
4 韩博宇,苏晓兰,郭宇,等.浅谈魏玮教授治疗脾胃病的用药经验[J].环球中医药,2018,11(7):1050-1051.
5 Forbes A,Kalantzis T.Crohn's disease:the cold chain hypothesis[J].Int J Colorectal Dis,2006,21(5):399-401.
6 Malekzadeh F,Alberti C,Nouraei M,et al.Crohn's disease and early exposure to domestic refrigeration[J].PLoS One,2009,4(1):e4288.
7 张敏,肖淑娟,王瑞,等.空调温度控制对住院病人胃寒症状的影响及护理干预[J].实用临床护理学电子杂志,2016,1(4):4.
8 张也,郭亚雄,李阳.小儿多见寒证探因及调护[J].陕西中医药大学学报,2019,42(4):63-65.
9 宋雅琳.慢性萎缩性胃炎中医体质辨析及证型分布研究[D].山东中医药大学,2018.
10 顾志坚,唐人彦,林江,等.莪连颗粒治疗脾虚瘀热型慢性萎缩性胃炎伴肠化生临床随机对照研究[J].上海中医药杂志,2015,49(4):40-43.
11 杨幼新,袁红霞,代二庆,等.慢性萎缩性胃炎癌前病变病理演变与中医证型的相关性[J].天津中医药大学学报,2006,(4):207-209.
12 李莉,朱蕾蕾,孙祝美,等.慢性萎缩性胃炎中医证型分布及幽门螺杆菌感染、胃黏膜病理变化情况分析[J].上海中医药杂志,2019,53(6):20-23.
13 王彦,魏玮.魏玮教授运用辛开苦降法治疗慢性萎缩性胃炎经验体会[J].云南中医学院学报,2013,36(1):50-51.
14 瞿先侯,杨洋,苏晓兰,等.半夏泻心汤为基础方辨治慢性萎缩性胃炎伴癌前病变的经验[J].环球中医药,2019,12(2):263-265.
15 Tang XD,Zhou LY,Zhang ST,et al.Randomized double-blind clinical trial of Moluodan for the treatment of chronic atrophic gastritis with dysplasia[J].Chin J Integr Med,2016,22(1):9-18.
16 杨静波,赵长普,张娟.乌梅丸对慢性萎缩性胃炎患者血清炎症指标、免疫功能的影响[J].中国实验方剂学杂志,2018,24(1):158-162.
17 Pimentel-Nunes P,Libanio D,Marcos-Pinto R,et al.Management of epithelial precancerous conditions and lesions in the stomach (MAPS Ⅱ):European Society of Gastrointestinal Endoscopy (ESGE),European Helicobacter and Microbiota Study Group (EHMSG),European Society of Pathology (ESP),and Sociedade Portuguesa de Endoscopia Digestiva (SPED) guideline update 2019[J].Endoscopy,2019,51(4):365-388.
18 向娟,薛智慧,陈果,等.针刺治疗慢性萎缩性胃炎的Meta分析[J].中医药导报,2016,22(15):75-78,83.
19 张勇,薛志欣,胡薇.针刺治疗慢性萎缩性胃炎合并幽门螺杆菌感染疗效观察[J].陕西中医,2016,37(8):1078-1079.
20 张迪,袁星星,王炳予,等.合募配穴灸法治疗慢性萎缩性胃炎临床观察[J].上海针灸杂志,2017,36(12):1401-1405.
21 周新桃,严芳琴.恒温雷火灸联合健康指导干预慢性萎缩性胃炎的疗效分析[J].实用中医内科杂志,2019(12):64-67.
22 王荟清,许可可,戴明.脾胃老十针治疗慢性萎缩性胃炎伴肠上皮化生的临床效果[J].中国医药导报,2018,15(33):106-109.
23 贾孟辉,马晓东,冯彩琴,等.中药穴位发泡疗法外治萎缩性胃炎60例[J].辽宁中医杂志,2011,38(12):2393-2395.
24 王伟,王永森,曹志群,等.芪莲舒痞膏穴位贴敷治疗慢性萎缩性胃炎癌前病变的临床疗效观察[J].时珍国医国药,2018,29(12):2953-2955.
25 韩晓江,杜锦辉,毕连宝,等.胃三针联合PPI三联疗法治疗幽门螺杆菌阳性慢性萎缩性胃炎疗效观察[J].上海针灸杂志,2020,39(1):11-14.
26 张玉红,马玲.针刺结合资生汤加减治疗脾胃虚弱型慢性萎缩性胃炎的临床效果[J].世界中医药,2017,12(11):2760-2763.
27 周翔禹,彭湃澜.肠化方配合老十针对慢性萎缩性胃炎伴肠上皮化生患者胃黏膜病理组织学及血清IL-23、PG1的影响[J].现代中西医结合杂志,2017,26(30):3338-3340,3410.
28 曾庆婷,杨改琴,左甲,等.针刺背俞穴配合埋线治疗慢性萎缩性胃炎的疗效观察[J].上海针灸杂志,2019,38(9):997-1001.
29 李嘉萍,李敏,王坤.穴位埋线配合灸法治疗慢性萎缩性胃炎临床研究[J].山东中医杂志,2019,38(10):933-937.
30 李依洁,郭宇,朱佳杰,等.穴位贴敷疗法防治消化系统疾病经验体会[J].河北中医,2016,38(9):1395-1397.
31 牛然,魏玮.辛开苦降联合活血化瘀法治疗慢性萎缩性胃炎体会[C].第二十五届全国中西医结合消化系统疾病学术会议,2013:1.
32 Sun Y,Wang S,Qi M,et al.Psychological distress in patients with chronic atrophic gastritis:the risk factors,protection factors,and cumulative effect[J].Psychol Health Med,2018,23(7):797-803.
33 Lefter R,Ciobica A,Timofte D,et al.A descriptive review on the prevalence of gastrointestinal disturbances and their multiple associations in autism spectrum disorder[J].Medicina (Kaunas),2019,56(1):11.
34 Spencer NJ,Hu H.Enteric nervous system:sensory transduction,neural circuits and gastrointestinal motility[J].Nat Rev Gastroenterol Hepatol,2020,17(6):338-351.
35 Budzyński J,K?opocka M.Brain-gut axis in the pathogenesis of Helicobacter pylori infection[J].World J Gastroenterol,2014,20(18):5212-5225.
36 Yu C,Su Z,Li Y,et al.Dysbiosis of gut microbiota is associated with gastric carcinogenesis in rats[J].Biomedicine,2020,126:110036.
37 Liu CC,Chen JL,Chang XR,et al.Comparative metabolomics study on therapeutic mechanism of electro-acupuncture and moxibustion on rats with chronic atrophic gastritis (CAG)[J].Sci Rep,2017,7(1):14362.
38 Tian G,Wu C,Li J,et al.Network pharmacology based investigation into the effect and mechanism of Modified Sijunzi Decoction against the subtypes of chronic atrophic gastritis[J].Pharmacol Res,2019,144:158-166.
39 Xu J,Zheng X,Cheng KK,et al.NMR-based metabolomics reveals alterations of electro-acupuncture stimulations on chronic atrophic gastritis rats[J].Sci Rep,2017,30(7):45580.
40 Yang T,Wang R,Zhang J,et al.Mechanism of berberine in treating Helicobacter pylori induced chronic atrophic gastritis through IRF8-IFN-γ signaling axis suppressing[J].Life Sciences,2020,248:117456.
41 Ws J,Zx G,Kc W,et al.Effect of Hewei-Decoction on chronic atrophic gastritis and eradication of Helicobacter pylori[J].World J Gastroenterol,2005,11(7):986-989.
42 Bai Y,Chen Y,Chen Y,et al.Efficacy of Banxia Xiexin decoction in a rat model of chronic atrophic gastritis[J].J Tradit Chin Med,2019,39(6):867-874.
43 Zhang Y,Li C,Sun S,et al.Screening and identification of molecular targets involved in preventing gastric precancerous lesions in chronic atrophic gastritis by Qilianshupi decoction[J].Evid Based Complement Alternat Med,2019,2019:5804710.
44 陈露,于佳宁,吕俊慧,等.中药萎胃康通过影响Hedgehog通路治疗慢性萎缩性胃炎的机制研究[J].中国中医基础医学杂志,2019,25(12):1668-1672.
45 李萍,李园,李可歆,等.基于生物分子网络探讨胃复春片治疗慢性萎缩性胃炎的作用机制研究[J].世界中西医结合杂志,2020,15(1):48-53.
46 吕尚斌,张怡,曾进浩,等.基于ERK/Cyclin E通路探讨健脾化瘀解毒方逆转CAG大鼠胃黏膜癌变效应机制[J].中华中医药学刊,2020,38(9):102-106,264-267.
47 王丽园,成映霞,段永强,等.香砂六君子汤对慢性萎缩性胃炎大鼠的作用研究[J].中国临床药理学杂志,2020,36(3):318-321.
48 张世洋,刘美辰,唐飞,等.人参、白术有效组分群对慢性萎缩性胃炎大鼠口腔、肠道菌群的影响[J].中成药,2020,42(1):48-54.
基本信息:
DOI:10.13210/j.cnki.jhmu.20200618.001
中图分类号:R259
引用信息:
[1]从禹,王亚杰,苏晓兰,等.“调枢通胃”法在慢性萎缩性胃炎中的应用及魏玮教授临床经验[J].海南医学院学报,2021,27(01):66-70.DOI:10.13210/j.cnki.jhmu.20200618.001.
基金信息:
中医药行业科研专项项目(201507001-09); 中国中医科学院自主项目(2211-035)~~
2020-06-30
2020-06-30
2020-06-30