海南医科大学学报

目的:通过文献研究探讨非酒精性脂肪肝(NAFLD)中医体质分布规律,确定该病常见的体质类型,为中医药防治NAFLD提供医学证据。方法:对建库至2020年4月在国内期刊发表的有关NAFLD与中医体质相关性的调查文献,以"非酒精性脂肪肝、中医体质"为检索词进行检索,依据纳排标准进行筛选、质量评价及数据提取。对纳入研究的文献采用stata16.0统计软件进行meta分析。结果:纳入16项研究,结果显示NAFLD患者中医体质类型比率及95%CI依次为痰湿质0.28(0.24,0.31)、湿热质0.16(0.13,0.20)、气虚质0.13(0.10,0.16)、平和质0.11(0.06,0.17)、气郁质0.08(0.06,0.10)、阴虚质0.08(0.06,0.10)、血瘀质0.07(0.04,0.09)、阳虚质0.06(0.04,0.08)、特禀质0.02(0.01,0.02)。结论:非酒精性脂肪肝患者常见的体质类型为痰湿质、湿热质、气虚质、平和质,特别是痰湿质与非酒精性脂肪肝关系最为密切。

Objective: To explore the distribution rules of non-alcoholic fatty liver(NAFLD) TCM constitution, and to determine the common constitution type of the disease so as to provide medical evidence for the prevention and treatment of NAFLD by Chinese medicine. Methods: The literature on the correlation between NAFLD and Chinese medicine constitution published in domestic journals from April 2020 to the beginning of the period was searched with "non-alcoholic fatty liver, Chinese medicine constitution" as the key words, and screened according to the criteria quality evaluation and data extraction. Meta-analysis was performed on the literature included in the study using stata16.0 statistical software. Results: A total of 16 studies were included, and the results showed that the ratio of TCM constitution types and 95% CI of NAFLD patients were phlegm and dampness 0.28(0.24, 0.31), damp and heat quality 0.16(0.13, 0.20), qi deficiency quality 0.13(0.10, 0.16), and moderate quality 0.11(0.06, 0.17), Qi depression quality 0.08(0.06, 0.10), Yin deficiency quality 0.08(0.06, 0.10), blood stasis quality 0.07(0.04, 0.09), Yang deficiency quality 0.06(0.04, 0.08), special characteristics quality 0.02(0.01,0.02). Conclusions: The common constitutional types of patients with nonalcoholic fatty liver are phlegm and dampness, dampness and heat, qi deficient, and moderate, especially phlegm and dampness are most closely related to nonalcoholic fatty liver.